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Student Competition I

Student Competition I

84 - Developing salivary gland ELISAs to measure human exposure to La Crosse virus vectors

Wednesday, March 5, 2025
9:30 AM – 9:40 AM AST
Location: 201
Abstract: La Crosse virus (LACV) is primarily vectored by three mosquito species— Aedes triseriatus, Ae. albopictus, and Ae. japonicus. Effective methods to measure vector exposure would be a significant advance. Salivary gland ELISAs of human sera (n=162) demonstrated higher mean optical densities for Ae. albopictus compared to Ae. triseriatus (P < 0.001) which is consistent with known endemic biting risk. Ongoing research is presented in the context of understanding disease risk and the impact of interventions