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Latin American Symposium II

Latin American Symposium II

158 - Efficacy and Persistence of Natular DT Mini Larvicide for the Control of Aedes aegypti Larvae in Brazil: A Study in Simulated Field Conditions with Local Populations and the Rockefeller Strain

Wednesday, March 5, 2025
2:45 PM – 2:55 PM AST
Location: 202
Abstract: Aedes aegypti is the primary vector of dengue, Zika, chikungunya, and urban yellow fever viruses, representing Brazil's serious public health issue. The combination of tropical climate and unplanned urbanization favors the proliferation of this mosquito, resulting in recurrent arbovirus outbreaks. Currently, the Ministry of Health uses NatularTM DT larvicide to treat breeding sites that cannot be eliminated, requiring the tablet to be split for containers smaller than 200 liters. To avoid this procedure, Clarke Mosquito Control developed NatularTM DT Mini, a new formulation suitable for containers up to 50 liters, with a labeled larvicidal persistence of up to 84 days. Thus, the present study verified in a multicentric test whether the residual effect of the product was similar in three different Brazilian regions: North (Macapá - AP), Northeast (Recife - PE), and Southeast (Rio de Janeiro - RJ). Tests in simulated field conditions were conducted in plastic containers holding 50 liters of water, treated with larvicide and weekly colonized with 50 L2 larvae of Ae. aegypti. Larval mortality was monitored at 24, 48, and 72 hours. Three times a week, 30% of the water volume was replaced, simulating household use. The results showed that NatularTM DT Mini maintained larval mortality above 80% for 12 weeks in Rio de Janeiro and weeks in Recife and Macapá, thus exceeding 84 days. In the control containers, larval mortality was below 20% in all three locations throughout the study. We conclude that NatularTM DT Mini is effective and persistent in controlling Ae. aegypti larvae, being a practical and efficient alternative for vector control programs.